Dependency’s level of nicotine tolerance

Our dependency’s level of nicotine tolerance (the amount of nicotine required daily in order to overcome acetylcholine receptor up-regulation and desensitization), combined with nicotine’s half-life to compel each of us to decide when during each day we would engage in replenishment in order to avoid experiencing early withdrawal anxieties. Possibly unaware we were doing so, we each established daily replenishment patterns that taught and conditioned our subconscious when to expect more nicotine. It was watching and remembering as use cues arriving via sight, smell, sound, taste, touch and emotions were quickly followed by arrival of new nicotine.